Common injection types
Corticosteroids
- What it is
- An anti-inflammatory medication injected into a joint, bursa, or soft-tissue area. Widely used in clinical practice for decades.
- How it generally works
- It suppresses local inflammation and swelling. Some patients experience pain relief and functional improvement for a limited period.
- Common uses in practice
- Moderate osteoarthritis, bursitis, frozen shoulder in the painful phase, tendon inflammations, and other inflammatory conditions depending on diagnosis and site. Common clinical uses also include degenerative joint changes (osteoarthritis) in joints such as the knee, trigger finger, shoulder bursitis or inflammation, and tendinopathies.
- What the evidence suggests
- Existing studies suggest pain relief for a portion of patients, especially in osteoarthritis and early inflammatory conditions. Results vary individually, and long-term benefit is not assured.
- Limits and considerations
- Should not be repeated too frequently into the same joint because of cumulative effects on cartilage, skin, and fat. Not appropriate when infection is suspected, fracture is untreated, or conservative care has not been tried appropriately.
Hyaluronic acid (viscosupplementation)
- What it is
- A substance similar to natural joint fluid, injected mainly into the knee. Sometimes described as joint "lubrication."
- How it generally works
- Aims to improve joint friction and cushioning. Some patients report gradual improvement after a course of injections.
- Common uses in practice
- Mild to moderate knee osteoarthritis, and occasionally other joints depending on local practice and guidelines.
- What the evidence suggests
- Long-term evidence remains debated. Studies and meta-analyses show that some patients benefit, but results are inconsistent and there is variation between products, protocols, and joints. It is not a substitute for rehabilitation or lifestyle change.
- Limits and considerations
- Less relevant in very advanced arthritis when the joint is already severely damaged. Cost, number of injections, and individual response all matter. Local swelling or temporary pain can occur.
PRP — platelet-rich plasma
- What it is
- A product derived from the patient's own blood. The process: a blood sample is taken, centrifugation separates the blood components, and the fraction rich in platelets and natural anti-inflammatory factors from the patient's body is re-injected into the affected area.
- How it generally works
- The idea is to deliver growth factors that may support tissue healing. The exact mechanism is still studied, and outcomes are not predictable in advance.
- Common uses in practice
- Tendinopathies, mild to moderate osteoarthritis, and other conditions under active research. Use varies between clinics and countries.
- What the evidence suggests
- Some studies are encouraging in selected settings, but overall evidence remains mixed. Some patients report improvement; others do not. There is no full agreement among the medical community that PRP is superior in every situation.
- Limits and considerations
- Cost, number of sessions, and lack of protocol uniformity. Not suitable for every diagnosis. Does not replace structural rehabilitation or surgery when mechanical damage is significant. Because PRP is derived from the patient's own blood, the likelihood of allergic or immune reaction is very low; the main practical caveat is mild, transient soreness at the injection site.
Diagnostic local anaesthetic injection
- What it is
- Injection of a numbing agent (for example lidocaine) into a structure suspected to be the pain source — joint, bursa, or other tissue.
- How it generally works
- If pain temporarily disappears after injection, that supports the hypothesis that the injected area is a significant source. If there is no change, another source should be considered.
- Common uses in practice
- Clarifying pain source when diagnosis is uncertain, distinguishing joint pain from referred pain, and guiding further treatment decisions.
- What the evidence suggests
- An established, evidence-based clinical method — a diagnostic tool in the clinical toolkit, not an intervention aimed at treating the underlying cause. It supports informed decisions together with examination and imaging.
- Limits and considerations
- Relief is temporary only. It does not treat the underlying cause. Results must be interpreted in full clinical context.
